Polypeptide ligands for targeting cartilage and methods of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/06 (2006.01) A61K 31/728 (2006.01) A61K 31/737 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/48 (2006.01) A61K 47/48 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2665839

Ligands that specifically bind to articular cartilage tissues are disclosed, including uses for targeting therapeutics towards articular cartilage tissue and new materials for articular cartilage. The ligands are effective in vivo to target therapeutic materials to articular cartilage.

La présente invention concerne des ligands qui se lient, de façon spécifique, aux tissus cartilagineux articulaires, ainsi que leur utilisation en matière de ciblage de thérapies en direction du tissu cartilagineux articulaire, de même que de ciblage de matériaux inédits en direction du cartilage articulaire. Les ligands se révèlent efficaces in vivo pour ce qui est de cibler des matériaux thérapeutiques en direction du cartilage articulaire.

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