Polypeptide-polymer conjugates having added and/or removed...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 9/96 (2006.01) A61K 47/48 (2006.01) C11D 3/37 (2006.01) C11D 3/386 (2006.01)

Patent

CA 2279986

The present invention relates to polypeptide-polymer conjugates having added and/or removed one or more attachment groups for coupling polymeric molecules on the surface of the polypeptide structure, a method for preparing polypeptide-polymer conjugates of the invention, the use of said conjugated for reducing the immunogenicity and allergenicity and compositions comprising said conjugate.

Cette invention a trait à des conjugats polypeptide-polymère à groupe (s) de fixation ajouté (s) et/ou retiré (s), ce ou ces groupes étant destiné (s) à coupler des molécules polymères à la surface de la structure polypeptidique. Elle concerne également un procédé de préparation des conjugats polypeptide-polymère susmentionnés, leur utilisation s'agissant de réduire capacité immunogène et pouvoir allergisant ainsi que des compositions contenant lesdits conjugats.

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