Polypeptide protracting tags comprising a tetrazole moiety

Details Polypeptide protracting tags comprising a tetrazole moiety Polypeptide protracting tags comprising a tetrazole moiety

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 3/08 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2572770

Method for increasing (protracting) half-life of LGP analogs in plasma and novel derivatives of such peptides based on covalently linking them to a tetrazole moiety which acts as a carboxylic acid bioisostere.

L'invention concerne une méthode pour prolonger la demi-vie de composés dans du plasma, et de nouveaux dérivés de tels composés.

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