Polypeptide recognized by anti hiv-1 gp41 antibodies...

Details Polypeptide recognized by anti hiv-1 gp41 antibodies... Polypeptide recognized by anti hiv-1 gp41 antibodies...

A - Human Necessities

61

K

A61K 39/21 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01)

Patent

CA 2679332

The invention relates to a polypeptiderecognized by anti HIV-1 gp41 antibodies isolated from Highly Exposed, non Infected Women, and epitopic fragments and conjugate thereof. Method of inducing antibodies neutralizing HIV-1 against HIV-1 is also contemplated.

L'invention concerne un nouveau polypeptide reconnu par des anticorps gp41 anti-VIH-1 isolé à partir de femmes non infectées, très exposées, sous forme entière, de fragments épitopiques ou de conjugués. Un procédé permettant d'induire des anticorps neutralisant le VIH-1, dirigés contre le VIH-1, est également décrit.

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