Polypeptide sequences of drug metabolizing enzymes and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) A01K 67/027 (2006.01) A61K 38/43 (2006.01) A61K 39/395 (2006.01) C07K 1/32 (2006.01) C07K 14/705 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/04 (2006.01) C12N 9/10 (2006.01) C12N 9/18 (2006.01) C12N 15/12 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2431203

The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.

La présente invention concerne des enzymes humaines métabolisant le médicament et des polynucléotides qui identifient et codent ces enzymes métabolisant le médicament. La présente invention se rapporte également à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ainsi qu'à des méthodes de diagnostic, de traitement ou de prévention des affections associées à l'expression aberrante des enzymes métabolisant le médicament.

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