Polypeptide variants with altered effector function

Details Polypeptide variants with altered effector function Polypeptide variants with altered effector function

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2577133

The invention provides polypeptides having IgG Fc regions with amino acid modifications that result in the polypeptides exhibiting altered Fc effector functions.

La présente invention concerne des polypeptides comprenant des régions IgG Fc présentant des modifications d'acides aminés permettant d'obtenir des polypeptides présentant des fonctions effectrices Fc modifiées.

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