Polypeptide with kd hmfg differentiation antigen binding...

Details Polypeptide with kd hmfg differentiation antigen binding... Polypeptide with kd hmfg differentiation antigen binding...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/745 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2095330

2095330 9207939 PCTABS00013 A polypeptide has the antibody binding activity of the 46K dalton HMFG differentiation antigen and/or homology to at least one of the light chains of clotting factors V and VIII and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for the polypeptide of the invention or a functional fragment thereof. In vivo and in vitro methods for therapy vaccination and detecting the presence of the polypeptide, the antibody, the DNA and RNA of the invention are provided. DNA and RNA sequences encode the polypeptide of the invention or fragments thereof and immunoassay kits comprise the antibodies and/or polypeptides of the invention.

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