Polypeptides

Details Polypeptides Polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/27 (2006.01) A61K 38/19 (2006.01) C07K 14/535 (2006.01) C12N 15/68 (2006.01) C12N 15/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2041454

ABSTRACT POLYPEPTIDES Derivatives of naturally occurring G-CSF having at least one of the biological properties of naturally occurring G-CSF, and a solution stability of at least 35% at 5 mg/ml are disclosed in which the derivative has at least Cys17 of the native sequence replaced by a Ser17 residue and Asp27 of the native sequence replaced by a Ser27 residue. Nucleotide sequences coding for part or all of the amino acid sequence of the derivatives of the invention may be incorporated into autonomously replicating plasmid or viral vectors employed to transform or transfect suitable procaryotic or eucaryotic host cells such as bacteria, yeast or vertebrate cells in culture.

Affiliated with

Also associated with

Rating

Polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1632640