Polypeptides and nucleic acids encoding same

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2394466

The present invention provides novel isolated MEMX polynucleotides and polypeptides encoded by the MEMX polynucleotides. Also provided are the antibodies that immunospecifically bind to a MEMX polypeptide or any derivative, variant, mutant or fragment of the MEMX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the MEMX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne des nouveaux polynucléotides MEMX et des polypeptides codés par ces polynucléotides MEMX. L'invention concerne également des anticorps se liant de manière immunospécifique à un polypeptide MEMX ou à un dérivé, une variante, un mutant ou un fragment de polypeptide, de polynucléotide ou d'anticorps MEMX. L'invention se rapporte en outre à des méthodes impliquant l'utilisation de ce polypeptide, de ce polynucléotide et de cet anticorps MEMX dans la détection et le traitement d'un large éventail d'états pathologiques et dans d'autres applications.

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