Polypeptides and nucleic acids encoding same

Details Polypeptides and nucleic acids encoding same Polypeptides and nucleic acids encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2306450

DNAs are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.

La présente invention concerne de l'ADN dont les gènes sont induits au moins par le Wnt-1. L'invention concerne également des molécules d'acide nucléique codant ces polypeptides, ainsi que des vecteurs et des cellules hôtes comprenant ces séquences d'acide nucléique. L'invention concerne en outre des molécules de polypeptides chimériques comprenant ces polypeptides fusionnés à des séquences de polypeptides hétérologues, des anticorps qui se lient à ces polypeptides, et des procédés de production de ces polypeptides.

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