Polypeptides and polynucleotides encoding same and use...

Details Polypeptides and polynucleotides encoding same and use... Polypeptides and polynucleotides encoding same and use...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2658972

An isolated polynucleotide is disclosed comprising a nucleic acid sequence encoding a polypeptide having an amino acid sequence of HIF-1alpha, the polypeptide being stably expressed and constitutively active. Isolated polypeptides encoded by same are also disclosed and uses thereof.

Polynucléotide isolé comprenant une séquence d'acides nucléiques codant un polypeptide à séquence d'acides aminés de HIF-1alpha, le polypeptide étant à expression stable et étant constitutivement actif. Également, polypeptides isolés codés par ce type de polynucléotide, et utilisations.

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