Polypeptides capable of interacting with the human...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/52 (2006.01) C07K 16/40 (2006.01) C12N 9/90 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2353304

The invention concerns novel polypeptides capable of interacting with the human topoisomerase III.alpha. and the nucleic acid sequences coding for said polypeptides. The invention also concerns a method for identifying compounds capable of interacting with said polypeptides and a method for identifying molecules capable of modulating the interaction of the topoisomerase III.alpha. with said polypeptides.

La présente invention concerne de nouveaux polypeptides capables d'interagir avec la topoisomérase III.alpha. humaine et les séquences d'acides nucléiques codant pour ces polypeptides. Elle concerne en outre une méthode d'identification de composés capables d'ineragir avec lesdits polypeptides ainsi qu'une méthode pour identifier des molécules capables de moduler l'interaction de la topoisomérase III.alpha. avec lesdits polypeptides.

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