Polypeptides comprising multimers of nuclear localization...

Details Polypeptides comprising multimers of nuclear localization... Polypeptides comprising multimers of nuclear localization...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 7/00 (2006.01) C07K 14/005 (2006.01) C07K 14/025 (2006.01) C07K 14/16 (2006.01) C07K 14/435 (2006.01) C12N 15/52 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2392490

Described are polypeptides comprising at least two peptide monomers comprising a nuclear localization sequence or a protein transduction domain and their use for transferring molecules into eukaryotic cells, as well as pharmaceutical compositions comprising the described polypeptides and processes for transferring molecules into eukaryotic cells.

On décrit des polypeptides comprenant au moins deux monomères de peptide comportant une séquence de localisation nucléaire ou un domaine de transduction de protéine et leur utilisation pour transférer des molécules dans des cellules eucaryotes, ainsi que des compositions pharmaceutiques contenant les polypeptides décrits et des procédés permettant de transférer des molécules dans des cellules eucaryotes.

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