C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/31 (2006.01) A61K 39/085 (2006.01) A61P 31/04 (2006.01) C12N 15/31 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2681035
The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF2695e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
L'invention concerne des polypeptides comprenant une séquence d'acides aminés structurellement en rapport avec SEQ ID N° : 1, et des utilisations de tels polypeptides. La SEQ ID N° : 1 est un dérivé tronqué du polypeptide de S. epidermidis de pleine longueur. Le polypeptide survenant naturellement de pleine longueur est désigné ci-après ORF2695e de pleine longueur. Un dérivé étiqueté His de la SEQ ID N° : 1 s'avère produire une réponse immune protectrice contre S. epidermidis.
Anderson Annaliesa S.
Cook James C. III
Mcclements William L.
Mcneely Tessie
Montgomery Donna L.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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