Polypeptides having kinase activity, their preparation and use

Details Polypeptides having kinase activity, their preparation and use Polypeptides having kinase activity, their preparation and use

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12P 9/00 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2111205

This invention relates to new polypeptides which exhibit kinase activity or, more specifically, which show phosphoinositide (PI)3-kinase activity. Such polypeptides are involved in pathways responsible for cellular growth and differentiation. An isolated polypeptide which possesses PI3-kinase activity when produced by recombinant production in insect cells is disclosed.

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