Polypeptides having neutrophil stimulating activity

Details Polypeptides having neutrophil stimulating activity Polypeptides having neutrophil stimulating activity

C - Chemistry, Metallurgy

07

K

C07K 14/80 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2723031

Neutrophil attracting and activating factors that may already exist in normal cells are located. Polypeptides having neutrophil stimulating activity were isolated from an extract originating from a normal porcine heart, whereby the invention was completed. The invention provides (a) a polypeptide consisting of the amino acid sequence of SEQ ID NO:1; (b) a polypeptide consisting of an amino acid sequence derived from the amino acid sequence of SEQ ID NO:3 by deletion, substitution, insertion or addition of one or more amino acids and having neutrophil stimulating activity; or (c) a polypeptide consisting of an amino acid sequence biologically equivalent to the amino acid sequence of said polypeptide (a) or (b).

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