Polypeptides homologous to vegf and bmp1

Details Polypeptides homologous to vegf and bmp1 Polypeptides homologous to vegf and bmp1

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2322792

The present invention involves the identification and preparation of vascular endothelial growth factor-E (VEGF-E). VEGF-E is a novel polypeptide related to vascular endothelial growth factor (VEGF) and bone morphogenetic protein 1. VEGF-E has homology to VEGF including conservation of the amino acids required for activity of VEGF. VEGF-E can be useful in wound repair, as well as in the generation and regeneration of tissue.

La présente invention concerne l'identification et la préparation du facteur E de croissance endothélial vasculaire (VEGF-E). Le VEGF-E est un nouveau polypeptide apparenté au facteur de croissance endothélial vasculaire (VEGF) et à la protéine 1 morphogénétique osseuse (BMP1). Le VEGF-E présente une homologie avec le VEGF, y compris pour le maintien des acides aminés nécessaires à l'activité de ce facteur. Le VEGF-E peut être utile aussi bien pour la cicatrisation que pour la génération et la régénération de tissus.

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