Polypeptides with an .alpha.-amylase-inhibiting action, a...

Details Polypeptides with an .alpha.-amylase-inhibiting action, a... Polypeptides with an .alpha.-amylase-inhibiting action, a...

C - Chemistry, Metallurgy

12

P

530/7.1, 195/122

C12P 21/04 (2006.01) C07K 7/50 (2006.01) C07K 14/36 (2006.01) C12N 1/20 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1230841

Abstract of the Disclosure Cyclic polypeptides of the formula I Image I in which z: represents Gln, Asn or Met; S: represents Ser or Thr; Y: represents Phe, Tyr or Asn and; AS: represents a polypeptide chain of 5 to 25 naturally occurring amino acids, which can in turn be substituted by further naturally occurring amino acids or peptide chains, excluding the .alpha.-amylase inactivator Tendamistat (HOE 467) and the .alpha.-amylase inhibitor isolated from the culture filtrate of Streptomyces violaceoruber ATCC 31209. The compounds have an .alpha.-amylase-inhibiting action.

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