Polypeptides with beta-secretase type activity

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/48 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 9/64 (2006.01) C12N 15/57 (2006.01) C12Q 1/37 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2330242

The invention concerns novel peptides and their pharmaceutical use. More particularly, the invention concerns novel polypeptides having a .beta.-secretase type activity characterised in that they are capable of specifically cleaving the natural .beta.-amyloid peptide precursor (APP).

La présente invention concerne de nouveaux polypeptides et leur utilisation pharmaceutique. Plus particulièrement, la présente invention concerne de nouveaux polypeptides possédant une activité de type .beta.-secrétase caractérisés en ce qu'ils sont capables de cliver de manière spécifique le précurseur naturel du peptide .beta.-amyloïde (APP).

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