C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61K 39/395 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2647524
The invention provides a polypeptide containing at least one IgG Fc region region, said polypeptide having a higher anti- inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.
La présente invention concerne un polypeptide contenant au moins une région IgG Fc, ledit polypeptide possédant une activité anti-inflammatoire accrue et une activité cytotoxique réduite par rapport à un anticorps non purifié. L'invention décrit également des procédés de production d'un tel polypeptide.
Nimmerjahn Falk
Ravetch Jeffrey V.
Yoshikatus Kaneko
Moffat & Co.
The Rockefeller University
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