Polypeptides with interleukin 8 receptor 1 (il8r1) binding...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2193526

This invention relates to a method of conferring IL8R1 specific binging domains on a polypeptide and to polypeptides that contain altered or unaltered IL8R1 specific binding domains. A method of using such polypeptides as agonists or antagonists is also provided, as well as a method producing such polypeptides.

L'invention concerne un procédé destiné à conférer des domaines de liaison spécifiques d'IL8R1 sur un polypeptide, ainsi que des polypeptides contenant des domaines de liaison spécifiques d'IL8R1 modifiés ou non modifiés. L'invention concerne également un procédé d'utilisation de ces polypeptides en tant qu'agonistes ou antagonistes, et un procédé de production desdits polypeptides.

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