Polyphenol containing compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/02 (2006.01) A61K 9/127 (2006.01) A61K 31/216 (2006.01)

Patent

CA 2672153

The present invention relates to liposomal compositions comprising polyphenol in the interior of a colloidal carrier, and especially to the use of such compositions in the treatment of cancer or in the inhibition of cancer growth and in the treatment of inflammatory and autoimmune conditions. More specifically, the invention relates to a method for targeting a polyphenol to tumor tissue, or to sites in the body requiring anti-inflammatory activity or activity against autoimmune conditions. Furthermore, the present invention describes a method of post-loading a polyphenol derivate such as caffeic acid into a liposome.

La présente invention concerne des compositions contenant du polyphénol à l'intérieur d'un vecteur colloïdal et concerne en particulier l'utilisation de telles compositions pour traiter le cancer ou pour inhiber le développement du cancer, ainsi que pour traiter des troubles inflammatoires et autoimmuns. Cette invention concerne plus spécifiquement une méthode de ciblage, par un polyphénol, d'un tissu tumoral ou de sites dans le corps nécessitant une activité anti-inflammatoire ou une activité contre les troubles autoimmuns.

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