C - Chemistry – Metallurgy – 08 – L
Patent
C - Chemistry, Metallurgy
08
L
C08L 5/00 (2006.01) A61K 33/00 (2006.01) A61K 47/48 (2006.01) C08K 5/32 (2006.01) C08K 5/34 (2006.01) C08L 79/02 (2006.01)
Patent
CA 2216696
A polymeric composition capable of releasing nitric oxide comprises a polysaccharide including a nitric oxide-releasing N2O.cndot. functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with nitric oxide is beneficial. The compositions can be used as and/or incorporated into implants, injectables, condoms, prosthesis coatings, patches, and the like for use in a wide variety of medical applications.
La présente invention concerne une composition polymérique capable de dégager du bioxyde d'azote, et qui comprend un polysaccharide incluant un groupe fonctionnel N2O2<->, lié au polymère, qui dégage du bioxyde d'azote; elle concerne des compositions pharmaceutiques qui comprennent la composition polymérique, et des procédés de traitement d'affections biologiques dans lesquelles l'adjonction de bioxyde d'azote est bénéfique. Ces compositions peuvent être utilisées comme, et/ou être incorporées à, des implants, des produits injectables, des préservatifs, des revêtements de prothèses, des timbres (patches) et autres, pour des utilisations médicales très variées.
Chakravarthy Debashish
Keefer Larry K.
Smith Daniel J.
Department O. F. Health And Human Services The United States Of America Represented By The Secretary
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
University Of Akron
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