Polysaccharide containing phosphorylcholine group and...

C - Chemistry – Metallurgy – 08 – B

Patent

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C08B 37/00 (2006.01) A61L 27/20 (2006.01) A61L 27/34 (2006.01) C07F 9/06 (2006.01) C08B 15/00 (2006.01) C08B 37/02 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2484840

The present invention is a method for manufacturing a phosphorylcholine group-containing polysaccharide wherein the aldehyde derivative-containing compound obtained by the oxidative ring-opening reaction of glycerophosphorylcholine is added to a polysaccharide containing amino groups as well as a new polysaccharide having phosphorylcholine groups obtained from this manufacturing method. The object of the present invention is to provide a phosphorylcholine group-containing polysaccharide that is superior in biocompatibility and moisture retention, and is useful as a polymer material for medical use, as well as a simple method of manufacturing it. The polysaccharide of the present invention is utilized, for example, in artificial organs, biomembranes, coating agents for medical tools, drug delivery, and in cosmetics.

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