Polysaccharides containing carboxyl functional groups...

C - Chemistry – Metallurgy – 08 – B

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Details

C08B 37/02 (2006.01) A61K 31/721 (2006.01) A61K 47/36 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2739546

The invention relates to a polysaccharide comprising carboxyl functional groups, at least one of which is substituted by a hydrophobic alcohol derivative. The invention also relates to a pharmaceutical composition containing one of the polysaccharides of the invention and at least one active principal. The invention further relates to a pharmaceutical composition characterised in that the active agent is selected from the group including proteins, glycoproteins, peptides and non-peptide therapeutic molecules. The invention also relates to the use of functionalised polysaccharides of the invention for preparing pharmaceutical compositions such as those described above.

L'invention concerne un polysaccharide comportant des groupes fonctionnels carboxyles dont un au moins est substitué par un dérivé d'alcool hydrophobe. L'invention concerne également une composition pharmaceutique comprenant l'un des polysaccharides selon l'invention et au moins un principe actif. Elle concerne également une composition pharmaceutique caractérisée en ce que le principe actif est choisi dans le groupe constitué par les protéines, les glycoprotéines, les peptides et les molécules thérapeutiques non-peptidiques. L'invention concerne également l'utilisation des polysaccharides fonctionnalisés selon l'invention pour la préparation de compositions pharmaceutiques telles que décrites précédemment.

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