Polysubstituted 2-amino-thiazole derivatives

Details Polysubstituted 2-amino-thiazole derivatives Polysubstituted 2-amino-thiazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 417/00 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61K 31/505 (2006.01) C07D 277/40 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2115805

Abstract of the disclosure Polysubstituted 2-amino-thiazole derivatives The invention relates to the use of a compound of formula Image (I) in which Y represents a 3-quinolyl group or a 2-indolyl group of formula Image in which - R is hydrogen, an acetyl group or a group CH2COOR', R' being hydrogen or a C1-C4-alkyl; - X is a (hetero)aryl radical chosen from 4-chloro- 2,6-dimethoxyphenyl, 2,6-dimethoxy-4-methylphenyl, 2,4,5-trimethoxyphenyl, 4-methyl-2,3,6-trimethoxyphenyl, 2,6-dimethoxy-4-ethylphenyl, 2,4,6-trimethoxy-5-chloro- phenyl, 2,4,6-trimethoxy-3-pyridyl, 2,4-dimethoxy-6- methyl-3-pyridyl, 6-chloro-2,4-dimethoxy-5-pyrmidinyl, 2,4,6-trimethoxy-5-pyrimidinyl, 5-chloro-2,4-dimethoxy- phenyl,5-chloro-2-methoxy-4-methylphenyl,2,5-dimethoxy- 4-methylphenyl, 4-trifluoromethyl-2,6-dimethoxyphenyl, 2,4-dimethoxy-5-methylphenyl, 5-ethyl-2,4-dimethoxyphenyl and 2,4-dimethoxyphenyl groups; - Z represents H, a C1-C4-alkyl or a benzyls with the limitation that Z is necessarily hydrogen when X is a phenyl radical substituted simultaneously at positions 2 and 6 or when X is a 3-pyridyl radical substituted simultaneously at positions 2 and 4 or when X is a 5-pyrimidinyl radical substituted simultaneously at positions 4 and 6; as well as its pharmaceutically acceptable salts and its solvates, for the preparation of medicinal products intended for combating complaints whose treatment necessitates a stimulation of the cholecystokinin receptors by a total or partial agonist effect. Figure none

Affiliated with

Also associated with

Rating

Polysubstituted 2-amino-thiazole derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polysubstituted 2-amino-thiazole derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polysubstituted 2-amino-thiazole derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1673309