C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/16 (2006.01) A61K 31/72 (1995.01)
Patent
CA 2075850
Disclosed is a polysulfate of a .beta.-cyclodexrin in which at least one of 7 D-glucose units constituting the .beta.-cyclodextrin is a unit represented by the formula (I - a): Image wherein R1 is an alkyl group having 1 to 8 carbon atoms, a phenyl-substituted lower alkyl group, a halogenophenyl-substituted lower alkyl group, a lower alkylphenyl-substituted lower alkyl group or a lower alkenyl group, or a salt thereof, which has excellent antiretrovirus activity and is useful as an antiretrovirus agent.
Divulgation concernant un polysulfate d'une bêta-cyclodextrine - dans lequel au moins l'une des 7 unités de D-glucose constituant la bêta-cyclodextrine est représentée par la formule (I - a) Image , où R1 est un groupe alkyle de 1 à 8 atomes de carbone, un groupe alkyle inférieur avec substitution par un phényle, un groupe alkyle inférieur avec substitution par un halogénophényle, un groupe alkyle inférieur avec substitution par un alkyl(inférieur)phényle, ou un groupe alcényle inférieur -, ou un sel de ce composé; il possède d'excellentes qualités antirétrovirales et est utile comme agent antirétroviral.
Kurita Hironori
Mori Haruyo
Morimoto Motoko
Moriya Tamon
Otake Toru
Marks & Clerk
Tanabe Seiyaku Co. Ltd.
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