Polysulfate of cyclodextrin derivative and process for...

C - Chemistry – Metallurgy – 08 – B

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167/199, 260/220

C08B 37/16 (2006.01) A61K 31/72 (1990.01)

Patent

CA 2038254

Abstract: A polysulfate of a cyclodextrin in which at least one of 6 to 8 D-glucose units constituting the cyclodextrin has been replaced by a unit represented by Formula(1): Image (I) wherein R is a group represented by the formula: 1) -OSO2R1, 2).-SR2, 3) Image , 4) -NHSO2R5 or 5) Image where R1 to R7 are defined in the specification, which have an excellent antiretrovirus activity, particularly an excellent proliferation-inhibiting activity against HIV.

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