Polyurethane foams for use in wound dressings

A - Human Necessities – 61 – L

Patent

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Details

A61L 15/26 (2006.01) A61L 15/42 (2006.01) C08G 18/10 (2006.01)

Patent

CA 2328424

The invention provides a method of forming a polyurethane foam suitable for use as a wound-contacting layer, said method comprising: mixing 1 part by weight of an isocyanate-capped prepolymer having from 0.5 to 4.8 meq. NCO groups/ g with from 0.4 to 1.0 parts by weight of water and an effective amount of a nonvolatile pharmaceutically acceptable acid to form a prepolymer mixture; allowing said prepolymer mixture to cure to form a foamed product; followed by drying the foamed product. The invention also provides acidified polyurethane foams obtainable by this method, and wound dressings comprising such foams.

L'invention se rapporte à un procédé pour former une mousse en polyuréthanne pouvant utilisée comme une couche en contact avec la blessure. Le procédé consiste en ce qui suit: on mélange 1 part en poids d'un prépolymère coiffé d'isocyanate et contenant de 0,5 à 4,8 mEq de groupes NCO / g avec 0,4 - 1,0 d'eau et avec une quantité efficace d'un acide non volatile pharmaceutiquement efficace, et ce pour former un mélange prépolymère; on permet à ce mélange prépolymère de durcir pour obtenir un produit en mousse; et l'on sèche ledit produit en mousse. L'invention concerne également des mousses de polyuréthanne acidifiée qui sont obtenues par ce procédé ainsi que des pansements pour blessures comportant ces mousses.

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