Polyvalent chimeric ospc vaccinogen and diagnostic antigen

Details Polyvalent chimeric ospc vaccinogen and diagnostic antigen Polyvalent chimeric ospc vaccinogen and diagnostic antigen

C - Chemistry, Metallurgy

07

K

C07K 14/195 (2006.01) A61K 39/02 (2006.01)

Patent

CA 2631733

A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections.

L'invention concerne une protéine recombinée polyvalente chimère utile comme vaccin et pour diagnostiquer la maladie de Lyme. La protéine chimère comprend des épitopes de la région de boucle 5 et/ou la région d'hélice alpha 5 de types de protéine C de surface extérieure (OspC). Les types d'OspC sont associés à des infections de mammifères par Borrelia.

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