Polyvalent rna-nanoparticle compositions

Details Polyvalent rna-nanoparticle compositions Polyvalent rna-nanoparticle compositions

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/713 (2006.01)

Patent

CA 2744207

The present invention concerns nanoparticles functionalized with duplex RNA for a variety of uses, including but not limited to gene regulation. More specifically, the disclosure provides a new strategy for conjugating RNA to a nanoparticle to achieve increased stability and activity.

La présente invention concerne des nanoparticules fonctionnalisées avec de lARN double brin pour diverses utilisations comprenant, entre autres, la régulation génique. Plus particulièrement, linvention concerne une nouvelle stratégie de conjugaison de lARN à une nanoparticule pour obtenir une augmentation de stabilité et dactivité.

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