C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/155 (2006.01) A61K 39/21 (2006.01) C12N 15/49 (2006.01)
Patent
CA 2733898
The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
La présente invention porte, d'une manière générale, sur une composition immunogène (par exemple, un vaccin) et, en particulier, sur une composition immunogène polyvalente, telle qu'un vaccin polyvalent contre le VIH, et sur des procédés d'utilisation de celles-ci. L'invention porte en outre sur des procédés qui utilisent un algorithme génétique pour créer des ensembles d'antigènes polyvalents appropriés pour une utilisation, par exemple, dans des stratégies de vaccination.
Fischer William
Hahn Beatrice H.
Haynes Barton F.
Korber Bette T.
Letvin Norman
Beth Israel Deaconness Medical Center
Duke University
Goudreau Gage Dubuc
Los Alamos National Security Llc
The University Of Alabama At Birmingham Research Foundation
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