C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 39/12 (2006.01) C07K 14/075 (2006.01) C07K 14/17 (2006.01) C12N 7/00 (2006.01) C12N 15/861 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2413265
The entire nucleotide sequence of porcine adenovirus serotype 5 (PAdV-5) is described as are methods of inserting heterologous nucleotide sequences, such as the TGEV S gene, into the E3 region of the virus. Vaccines and methods of preparing vaccines with the recombinant adenovirus are described as well as applications of the recombinant virus and vaccines.
La présente invention concerne la totalité de la séquence nucléotidique du sérotype 5 d'adénovirus porcin (PAdV-5) ainsi que des procédés d'insertion de séquences nucléotidiques hétérologues, telles que le gène TGEV S, dans la région E3 du virus. L'invention concerne également des vaccins et des procédés de préparation de vaccins au moyen de l'adénovirus de recombinaison ainsi que des applications du virus de recombinaison et des vaccins.
Nagy Eva
Nagy Miklos
Tuboly Tamas
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Nagy Eva
Nagy Miklos
Tuboly Tamas
University Of Guelph
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