Porcine animals lacking any expression of functional alpha...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/071 (2010.01) C12N 15/873 (2010.01) A01K 67/027 (2006.01) A61K 35/12 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/02 (2006.01) C12N 15/54 (2006.01) C12N 15/90 (2006.01) C12Q 1/04 (2006.01)

Patent

CA 2496761

The present invention is a porcine animal, tissue, organ, cells and cell lines, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha 1,3GT). These animals, tissues, organs and cells can be used in xenotransplantation and for other medical purposes.

La présente invention concerne un porcin, un tissu, un organe, des cellules et des lignées cellulaires provenant d'un porcin, ne présentant aucune expression de l'alpha 1,3-galactosyltransférase (alpha 1,3GT) fonctionnelle. Ces animaux, ces tissus, ces organes et ces cellules peuvent être utilisés lors de xénotransplantation ainsi que pour d'autres applications médicales.

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