Porcine mhc class i genes and uses thereof

Details Porcine mhc class i genes and uses thereof Porcine mhc class i genes and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) C07K 14/74 (2006.01) C12Q 1/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2301169

The invention features porcine MHC class I genes and the use of the polypeptides they encode in induction of graft-specific immunological tolerance in recipients of porcine cell or organ transplant and the generation of certain useful antibodies.

Cette invention se rapporte à des gènes de classe I MHC porcins et à l'utilisation des polypeptides qu'ils codent pour induire une tolérance immunologique spécifique de la greffe chez des receveurs de greffes de cellules ou d'organes de porcs, ainsi qu'à la production de certains anticorps utiles.

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