Porous beta-tricalcium phosphate granules and methods for...

Details Porous beta-tricalcium phosphate granules and methods for... Porous beta-tricalcium phosphate granules and methods for...

C - Chemistry, Metallurgy

01

B

C01B 25/32 (2006.01) A61L 27/12 (2006.01) A61L 27/46 (2006.01) A61L 27/54 (2006.01) A61L 27/56 (2006.01) C04B 35/447 (2006.01)

Patent

CA 2659188

A porous .beta.-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 µm, preferably 50-125 µm The porous .beta.-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous .beta.-TCP, and a bioactive agent and a binder. The invention also provides an implementable prosthetic device comprising a prosthetic implant having a surface region, a porous 0-TCP material disposed on the surface region optionally comprising at least a bioactive agent or a binder. Methods of producing the porous 0-TCP material and including bone formation are also provided.

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