Porous calcium phosphate cement

A - Human Necessities – 61 – L

Patent

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A61L 24/02 (2006.01) C04B 12/02 (2006.01) C04B 28/34 (2006.01) C04B 38/02 (2006.01) C04B 38/10 (2006.01)

Patent

CA 2394100

A kit and a method for making a porous cement which self sets to hydroxyapatite and has an interconnected porosity is produced by mixing a calcium source and a phosphate source with a carbonate source and mixing this powdered component with a liquid component having an acid component. The liquid component comprises water on an aqueous solution containing an acid. The acid and the carbonate react to form carbon dioxide thereby producing an interconnected porosity in the normally solid self-hardening bone cement. The method requires only a relatively low weight percent of the acid and base to be mixed with the liquid and powder cement components.

La présente invention concerne un kit et un procédé permettant de préparer un ciment poreux qui prend de façon autonome sur une hydroxyapatite et qui présente une porosité interconnectée. Ce ciment est obtenu par le mélange d'une source de calcium et d'une source de phosphate avec une source de carbonate, et par le mélange de ce composant de poudre avec un composant liquide possédant un composant acide. Le composant liquide comprend de l'eau sur une solution aqueuse contenant un acide. L'acide et le carbonate réagissent de façon à former du dioxyde de carbone, produisant ainsi une porosité interconnectée dans le ciment de l'os normalement solide à durcissement autonome. Ce procédé ne nécessite qu'un faible pourcentage en masse d'acide et de base à mélanger avec les composants liquide et de ciment en poudre.

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