Porous polymer scaffolds for tissue engineering

Details Porous polymer scaffolds for tissue engineering Porous polymer scaffolds for tissue engineering

A - Human Necessities

61

L

A61L 27/14 (2006.01) A61L 27/56 (2006.01)

Patent

CA 2370810

Biodegradable and biocompatible porous scaffolds are characterized by a substantially continuous polymer phase, having a highly interconnected bimodal distribution of open pore sizes with rounded large pores of about 50 to about 500 microns in diameter and rounded small pores less than 20 microns in diameter, wherein the small pores are aligned in an orderly linear fashion within the walls of the large pores. Methods of preparing polymeric tissue scaffolds are also disclosed.

L'invention concerne des échafaudages poreux biodégradables et biocompatibles caractérisés par une phase polymère sensiblement continue qui présente une distribution bimodale à degré d'interconnexion élevé de la taille des pores ouverts, et comprend de grands pores arrondis d'un diamètre de 50 à 500 microns environ et de petits pores arrondis d'un diamètre inférieur à 20 microns, les petits pores étant alignés selon un mode linéaire ordonné dans les parois des grands pores.

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