Porous tissue scaffoldings for the repair or regeneration of...

A - Human Necessities – 61 – L

Patent

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A61L 27/00 (2006.01) A61F 2/28 (2006.01) A61F 2/30 (2006.01) A61L 27/18 (2006.01) A61L 27/38 (2006.01) A61L 27/50 (2006.01) A61L 27/56 (2006.01) A61L 31/06 (2006.01) A61L 31/14 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2313067

The present patent describes a three-dimensional inter- connected open cell porous foams that have a gradient in composition and/or microstructure through one or more directions. These foams can be made from a blend of absorbable and biocompatible polymers that are formed into foams having a compositional gradient transitioning from predominately one polymeric material to predominately a second polymeric material. These gradient foams are particularly well suited to tissue engineering applications and can be designed to mimic tissue transition or interface zones.

Dans le présent brevet, on divulgue des mousses poreuses tridimensionnelles à alvéoles ouvertes interconnectées qui comporte un gradient de composition et/ou de microstructure dans une ou plusieurs directions. Ces mousses peuvent être produites à partir d'un mélange de polymères biocompatibles et absorbables pour former des mousses ayant un gradient de composition allant d'une matière polymère prédominante à une deuxième matière polymère prédominante. Ces mousses à gradient conviennent particulièrement bien à des applications techniques de tissu et peuvent être conçues afin d'imiter des zones interfaces ou de transition de tissus.

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