C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/22 (2006.01) A61K 31/40 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2645063
The present invention relates to novel porphyrin derivates of formula (I), especially to porphyrins which carry substituted phenyl moieties in meso- position. The porphyrin derivates of the invention are useful as photosensitizers in photodynamic therapy (PDT), especially in photodynamic tumor therapy. Due to their excellent photophysical properties the compounds of formula I are extremely efficient in photodynamic treatment.
La présente invention concerne de nouveaux dérivés de porphyrine de formule (I), en particulier des porphyrines qui portent des groupements phényle substitués en position méso. Les dérivés de porphyrine selon l'invention peuvent être employés en tant que photosensibilisants en thérapie photodynamique (PDT), en particulier en thérapie tumorale photodynamique. Du fait de leurs excellentes propriétés photophysiques, les composés de formule I sont extrêmement efficaces en traitement photodynamique.
Ermilov Eugeny
Jasinski Stefan
Jux Norbert
Roeder Beate
Deeth Williams Wall Llp
Friedrich-Alexander-Universitaet Erlangen-Nuernberg
Humboldt-Universitaet Zu Berlin
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