Porphyrin-polyamine conjugates for cancer therapy

Details Porphyrin-polyamine conjugates for cancer therapy Porphyrin-polyamine conjugates for cancer therapy

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/409 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2490298

Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.

L'invention concerne des composés conjugués de porphyrine-polyamine ayant des effets anticancéreux et anti-tumoraux. La fraction porphyrine est localisée sélectivement dans les tumeurs et la fraction polyamine sert d'agent cytotoxique. Des méthodes de fabrication et d'utilisation de composés conjugués porphyrine-polyamine sont également décrites.

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