C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 39/40 (2006.01) A61P 1/02 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C07K 14/195 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2407603
The present invention relates to soluble P.gingivalis polypeptides derived from PG32 and PG33 and to polynucleotides encoding these polypeptides. The P.gingivalis polypeptides and nucleotides can be used in compositions for use in raising an immune response in a subject against P.gingivalis and treating or preventing or reducing the severity of the condition known as periodontitis or in other conditions related to infection with P.gingivalis.
La présente invention concerne des polypeptides de P.gingivalis solubles issus de PG32 et PG33, ainsi que des polynucléotides codant ces polypeptides. On peut utiliser les polypeptides et nucléotides de P.gingivalis dans des compositions destinées à augmenter la réponse immunitaire chez un sujet contre P.gingivalis et à traiter, prévenir ou réduire la gravité de la parodontite liée à l'infection par P.gingivalis.
Barr Ian George
Czajkowski Larissa
Ross Bruce Carter
Csl Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The University Of Melbourne
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