Portable ribozyme cassettes, dna sequences containing them,...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/62 (2006.01) A01N 63/02 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2088154

Abstract Portable ribozyme cassettes, DNA sequences containing them, ribozymes encoded by these DNA sequences, and compositions containing these ribozymes Portable ribozyme cassettes are described which can be incorporated into restriction enzyme cleavage sites of any desired DNA sequence. Thus, highly selective ribozymes (antizymes) are provided. Additionally, methods for the production of these portable ribozyme cassettes, DNA sequences containing them and encoding biologically active ribozymes are described. Also described are compositions containing such ribozymes or DNA sequences encoding them.

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