Positioning and electrophysiological characterization of...

G - Physics – 01 – N

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G01N 33/487 (2006.01) G01N 27/403 (2006.01) G01N 30/64 (2006.01) G01N 27/04 (2006.01)

Patent

CA 2316966

The invention relates to a measuring device which permits a very simple positioning of cells and vesicles respective of cell membranes on planar carriers. The invention also relates to a corresponding highly efficient method for the positioning and electric characterization of such membranes with a consistently high signal-to-noise ratio. In addition, statements concerning interactions of substances with lipid membranes respective of materials bonded thereon or therein respective of signal transduction mechanisms connected thereto are possible.

L'invention concerne un dispositif de mesure permettant un positionnement très facile de cellules et de vésicules, ainsi que des membranes cellulaires sur des supports planaires. L'invention concerne en outre un procédé correspondant très efficace de positionnement et de caractérisation électrique de membranes de ce type avec un rapport signal-bruit élevé de manière constante. Ce système permet de faire des propositions concernant des interactions de substances avec des membranes lipidiques respectivement de substances liées dessus ou dedans, respectivement de mécanismes de transduction de signaux en relation avec.

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