Post-operative control of cardiac arrhythmia by modification...

Details Post-operative control of cardiac arrhythmia by modification... Post-operative control of cardiac arrhythmia by modification...

A - Human Necessities

61

K

A61K 31/765 (2006.01) A61B 18/00 (2006.01) A61K 31/734 (2006.01) A61K 35/12 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 45/00 (2006.01) A61L 31/14 (2006.01) A61M 5/00 (2006.01) A61N 1/362 (2006.01)

Patent

CA 2652295

To control cardiac arrhythmias such as atrial fibrillation post-operatively, various non-ablative agents include polymers, fibroblasts, neurotoxins, and growth factors are introduced into one or more cardiac fat pads into the atrioventricular nodal fat pad in proximity to the autonomic ganglia therein. Any desired technique may be used for introducing the agent, including injection. The sinoatrial nodal fat pad target site and the atrioventricular nodal fat pad target site are identified using a stimulator, which may have electrodes coupled thereto or which may coupled to electrodes built into a delivery system.

Aux fins de commander une arythmie cardiaque telle qu'une fibrillation auriculaire postopératoire, divers agents non ablatifs comprenant des polymères, des fibroblastes, des neurotoxines et des facteurs de croissance sont introduits dans un ou plusieurs coussinets adipeux du coeur dans le coussinet adipeux nodal auriculoventriculaire à proximité des ganglions végétatifs. On peut utiliser toute technique souhaité pour introduire cet agent, y compris l'injection. Le site cible de coussinet adipeux nodal sino-auriculaire et le site cible de coussinet adipeux nodal auriculoventriculaire sont identifiés au moyen d'un stimulateur, qui peut posséder des électrodes reliées à ces sites ou qui peut être relié à des électrodes intégrées dans un système d'apport.

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