Potent immunostimulatory component in microalgae extract

C - Chemistry – Metallurgy – 07 – K

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C07K 14/405 (2006.01) A61K 38/16 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2662550

Potent immunostimulatory lipoproteins have been identified within the following microalgae and extracts thereof: Spirulina species, Chlorella species, Haematococcus pluvialis and Aphanizomenon flos-aquae. This lipoprotein component can be extracted from the microalgae or microalgae spent material using various procedures. The resulting preparations exhibit extremely potent immunostimulatory activity. These preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function. Methods are also disclosed for the chemical and bioactivity based standardization of immunostimulatory microalgae extracts and the raw material.

L'invention concerne des lipoprotéines à puissante activité immunostimulante qui ont été identifiées dans les micro-algues suivantes et leurs extraits : espèces Spirulina, espèces Chlorella, Haematococcus pluvialis et Aphanizomenon flos-aquae. Ces composants lipoprotéiques peuvent être extraits des micro-algues ou du matériel de micro-algues par différents procédés. Les préparations obtenues affichent une activité immunostimulante extrêmement puissante. Ces préparations sont potentiellement utiles sous forme de préparation botanique ou pharmaceutique destinée à améliorer la fonction immunitaire. L'invention concerne également des procédés de standardisation chimique ou bioactive des extraits de micro-algues immunostimulants et de la matière première.

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