Potentiation of temozolomide in human tumour cells

Details Potentiation of temozolomide in human tumour cells Potentiation of temozolomide in human tumour cells

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2153775

The toxicity of temozolomide an anti-tumour agent useful in the treatment of various mammalian neoptasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O6-benzylguanine.

La toxicité de la témozolomide qui est un agent anti-tumoral utilisé dans le traitement de divers néoplasmes mammaliens, est augmentée par administration préalable d'un agent inhibiteur de l'ATase, c'est-à-dire de la benzylguanine-O6.

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