Potentiation of the activation of high-molecular-mass prodrugs

Details Potentiation of the activation of high-molecular-mass prodrugs Potentiation of the activation of high-molecular-mass prodrugs

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2536442

The invention relates to a modified prodrug form. According to the invention, a typical prodrug form comprises a bulky group, a spacer, a cleavable structure in the circulatory system and a therapeutic agent or a marker, said spacer enabling or facilitating the cleavage of the cleavable structure.

La présente invention a pour objet une forme modifiée d'une prodrogue. Une forme typique de prodrogue selon l'invention comprend un groupe encombrant, un espaceur, une structure clivable dans l'appareil circulatoire et un agent thérapeutique ou un marqueur; l'espaceur permettant ou facilitant le clivage de la structure clivable.

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