Powder formulation disintegrating system and method for dry...

A - Human Necessities – 61 – M

Patent

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Details

A61M 15/00 (2006.01) A61M 11/00 (2006.01)

Patent

CA 2445892

For improving efficiency of the application of medical powder formulations a disintegration means for dry powder inhalers is proposed, comprising a substantially cylindrical air circulation chamber (3) with a height being smaller than its diameter, and at least two air supply channels (2, 9) which enter the chamber (3) as tangents to its cylindrical wall (5) at generally opposite sides of this wall (5), suitable for creating a circular air flow pattern inside the chamber (3), both air channels (2, 9) either having different inlets or alternatively sharing the same inlet which is split up, so as to have one passageway (2) for traversing the dose measuring or dose supplying region of the inhaler for enabling the powder quantity of a single dose dragged into the circulation chamber (3) by air flowing through this passageway (2), and the other passageway to serve as a bypass channel (9) towards the circulation chamber (3) suitable for accelerating the particles and creating a more symmetrical flow pattern inside said chamber (3), and a method.

L'invention concerne un dispositif de désintégration pour inhalateurs de poudre rendant plus efficace l'application de formulations médicales de poudre. Ce dispositif comporte une chambre (3) de circulation d'air sensiblement cylindrique qui présente une hauteur inférieure à son diamètre, et au moins deux canaux (2, 9) d'entrée d'air qui pénètrent dans la chambre (3) comme tangentes à la paroi cylindrique (5) de celle-ci, sur des côtés généralement opposés de cette paroi (5), afin de produire un motif d'écoulement d'air circulaire à l'intérieur de la chambre (3) ; les deux canaux (2, 9) d'air comportent soit des orifices d'entrée différents, soit partagent le même orifice d'entrée divisé, de manière à former un seul passage (2) traversant la région de mesure ou d'administration de dose de l'inhalateur pour permettre d'entraîner dans la chambre (3) de circulation, grâce à l'écoulement d'air traversant le passage (2), la quantité de poudre correspondant à une dose ; l'autre passage, qui sert de canal (9) de dérivation vers la chambre (3) de circulation, permet d'accélérer les particules et de former un motif d'écoulement plus symétrique à l'intérieur de la chambre (3). L'invention concerne aussi un procédé.

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