Powder processing with pressurized gaseous fluids

Details Powder processing with pressurized gaseous fluids Powder processing with pressurized gaseous fluids

A - Human Necessities

61

K

A61K 9/16 (2006.01)

Patent

CA 2462338

Disclosed is a method of small particle precipitation, retention and dispersion of a solid or semi-solid material onto or into a carrier material. In this method, solute particles areprecipitated from a pressurized gaseous fluid solution or a liquid solution and effectivelyretained and dispersed within a carrier material. This technique can be advantageously used in pharmaceutical processing to produce a blend of solid or semi-solid material particlesand carrier material, a granulation of the solid or semi-solid material particles with carrier material, carrier material partially or fully coated with the solid or semi-solid material particles,or mixtures thereof.

La présente invention concerne un procédé de précipitation de petites particules, de rétention et de dispersion d'un matériau solide ou semi-solide sur ou dans un matériau porteur. Dans ce procédé, des particules de soluté sont précipitées à partir d'une solution de fluide gazeux sous pression ou d'une solution liquide et ces particules sont efficacement retenues et dispersée dans un matériau porteur. On peut avantageusement utiliser cette technique dans un traitement pharmaceutique pour produire un mélange de particules de matériau solide ou semi-solide et un matériau porteur, une granulation de ces particules de matériau solide ou semi-solide avec un matériau porteur, un matériau porteur partiellement ou complètement revêtu de ces particules de matériau solide ou semi-solide ou d'un mélange de celles-ci.

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